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Gruppenleiter

Apl. Prof. Dr. Erich Glawischnig
Apl. Prof. Dr. Erich Glawischnig

Gruppenleiter

Tel.: +49 (0) 9421 187-323
E-Mail: glawischnig@tum.de

TUM Campus Straubing
Schulgasse 22
94315 Straubing

Schulgasse 22 Raum: 0.009

Vita

 

Lebenslauf

  • seit 2018 Gruppenleiter an der Professur Mikrobielle Biotechnologie
  • 2017-2018 Wissenschaftlicher Mitarbeiter und Dozent am Lehrstuhl für Chemie Biogener Rohstoffe.
  • Verantwortlicher für Staatsexamina Lehramt Biologie im Bereich Botanik (2016/2017)
  • Bestellung zum außerplanmäßigen Professor (2015)
  • 2012-2017 DFG Heisenbergstipendiat (TUM, WZW)
  • Habilitation und Ernennung zum Privatdozenten (2007)
  • 2002-2012 Arbeitsgruppenleiter am Lehrstuhl für Genetik (TUM)
  • 2000-2002 EMBO-stipendiat am Zentrum für Molekulare Pflanzenphysiologie (Halkier Lab), Kopenhagen, Dänemark
  • Hans-Fischer-Gedächtnispreis (1998)
  • Promotion bei Prof. Gierl zum Thema ”Biochemische und genetische Aufklärung der Biosynthese von Benzoxazinonen in Zea mays” (mit Auszeichnung, 1997)
  • 1994-2000 Wissenschaftlicher Mitarbeiter am Lehrstuhl für Genetik (TUM)
  • 1987-1993 Studium der Biologie (Diplom), Hauptfach Mikrobiologie (TU München)

Forschung

  • Pflanzlicher Tryptophanstoffwechsel, insbesondere Biosynthese Pathogen-induzierter Abwehrstoffe
  • Pflanzliche Cytochrom P450-Enzmye

Publikationen

  • Rahikainen M, Trotta A, Alegre S, Pascual J, Vuorinen K, Overmyer K, Moffatt B, Ravanel, S, Glawischnig E, Kangasjärvi S (2017). PP2A-B’γ modulates foliar trans-methylation capacity and formation of 4-methoxy-indol-3-yl-methyl glucosinolate in Arabidopsis leaves. Plant Journal, 89(1):112-127.
  • Frerigmann H, Piślewska-Bednarek M, Sánchez-Vallet A, Molina A, Glawischnig E, Gigolashvili T, Bednarek P. (2016) Regulation of pathogen triggered tryptophan metabolism in Arabidopsis thaliana by MYB transcription factors, Molecular Plant, 9(5):682-95.
  • Chapman A, Lindermayr C, Glawischnig E. (2016) Expression of antimicrobial peptides under control of a camalexin-biosynthetic promoter confers enhanced resistance against Pseudomonas syringae. Phytochemistry, 122:76-80.
  • Frerigmann H, Glawischnig E, Gigolashvili T (2015) The role of MYB34, MYB51 and MYB122 in the regulation of camalexin. Frontiers in Plant Science, 6:654.
  • Peskan-Berghöfer T, Vilches-Barro A., Müller TM, Glawischnig E, Reichelt M, Gershenzon J, Rausch T (2015). Sustained exposure to ABA enhances colonization potential of the mutualist fungus Piriformospora indica on Arabidopsis thaliana roots. New Phytologist, 208, 873-886.
  • Müller TM, Böttcher C, Morbitzer R, Götz CC, Lehmann J, Lahaye T, Glawischnig E (2015) TALEN-mediated generation and metabolic analysis of camalexin-deficient cyp71a12 cyp71a13 double knockout lines. Plant Physiology 168: 849-858.
  • Mucha S, Walther D, Müller T, Hincha DK, Glawischnig E (2015) Substantial reprogramming of the Thellungiella salsuginea transcriptome in response to UV and silver nitrate challenge. BMC Plant Biol 15:137
  • Böttcher C, Chapman A, Fellermeier F, Choudhary M, Scheel D, Glawischnig E (2014) The biosynthetic pathway of indole-3-carbaldehyde and indole-3-carboxylic acid derivatives in Arabidopsis thaliana. Plant Physiology 165(2):841-853.
  • Weis C, Pfeilmeier S, Glawischnig E, Isono E, Pachl F, Hahne H, Küster B, Eichmann R, Hückelhoven R (2013) Co-immunoprecipitation-based identification of putative BAX INHIBITOR-1-interacting proteins involved in cell death regulation and plant – powdery mildew interactions. Mol Plant Pathol. 14(8):791-802.
  • Mewis I, Khan MAM, Glawischnig E, Schreiner M, Ulrichs C. (2012) Water Stress Mediated Alteration in Plant Response of Arabidopsis thaliana (L.) to Aphid Feeding. PLoS ONE, 7(11):e48661.
  • Nongbri PL, Johnson JM, Sherameti I, Glawischnig E, Halkier BA, Oelmüller R. (2012) Indole-3-acetaldoxime derived compounds restrict root colonization in the beneficial interaction between Arabidopsis roots and the endophyte Piriformospora indica. Mol Plant Microbe Interact, 25, 1186-1197
  • Pedras MS, Yaya E, Glawischnig E. (2011) The phytoalexins from cultivated and wild crucifers: Chemistry and biology. Nat Prod Rep, 28, 1381-1405
  • Yin R, Frey M, Gierl A, Glawischnig E. (2010) Plants contain two distinct classes of functional tryptophan synthase beta proteins. Phytochemistry, 71, 1667-1672
  • Böttcher C, Westphal L, Schmotz C, Prade E, Scheel D, Glawischnig E. (2009) The multifunctional enzyme, CYP71B15 (PHYTOALEXIN DEFICIENT 3), converts cysteine-indole-3-acetonitrile to camalexin in the indole-3-acetonitrile metabolic network of Arabidopsis thaliana. Plant Cell, 21, 1830-1845
  • Rauhut T, Glawischnig E. (2009) Evolution of camalexin and structurally related indolic compounds. Phytochemistry, 70, 1638-1644
  • Rauhut T, Luberacki B, Seitz HU, Glawischnig E. (2009) Inducible expression of a Nep1-like protein serves as a model trigger system of camalexin biosynthesis. Phytochemistry, 70, 185-189
  • Kriechbaumer V, Weigang L, Fießelmann A, Letzel T, Frey M, Gierl A, Glawischnig E. (2008) Characterisation of the tryptophan synthase alpha subunit in maize. BMC Plant Biology, 8, 44
  • Rauhut T, Spiteller P, Eisenreich W, Spiteller M, Glawischnig E. (2008) The biosynthetic origin of BE-10988 in Streptomyces spec. BA10988. J Org Chem, 73, 5279-5286
  • Siemens J, Glawischnig E, Ludwig-Müller J. (2008) Indole glucosinolates and camalexin do not influence the development of the clubroot disease in Arabidopsis thaliana. J Phytopathology, 156, 322-337
  • Kriechbaumer V, Park WJ, Piotrowski M, Meeley RB, Gierl A, Glawischnig E. (2007) Maize nitrilases have a dual role in auxin homeostasis and b-cyanoalanine hydrolysis. J Exp Botany, 58, 4225-4233
  • Gust AA, Biswas R, Lenz HD, Rauhut T, Ranf S, Kemmerling B, Götz F, Glawischnig E, Lee J, Felix G, Nürnberger T. (2007) Bacteria-derived peptidoglycans constitute pathogen-associated molecular patterns triggering innate immunity in Arabidopsis. J Biol Chem, 282, 32338-32348
  • Nafisi M, Goregaoker S, Botanga CJ, Glawischnig E, Olsen CE, Halkier BA, Glazebrook J 2007). Arabidopsis cytochrome P450 monooxygenase 71A13 catalyzes the conversion of indole-3-acetaldoxime in camalexin synthesis. Plant Cell, 19, 2039-2052
  • Glawischnig E. (2007) Camalexin. Phytochemistry, 68, 401-406
  • Schuhegger R, Rauhut T, Glawischnig E. (2007) Regulatory variability of camalexin biosynthesis. J Plant Physiology, 164, 636-644
  • Qutob D, Kemmerling B, Brunner F, Küfner I, Engelhardt S, Gust AA, Luberacki B, Seitz H-U, Stahl D, Rauhut T, Glawischnig E, Schween G, Lacombe B, Watanabe N, Lam E, Schlichting R, Scheel D, Nau K, Dodt G, Hubert D, Gijzen M, Nürnberger T. (2006) Phytotoxicity and innate immune responses induced by Nep1-like proteins. Plant Cell, 12, 3721-3744
  • Schuhegger R, Nafisi M, Mansourova M, Petersen BL, Olsen CE, Svatos A, Halkier BA, Glawischnig E. (2006) CYP71B15 (PAD3) catalyzes the final step in camalexin biosynthesis. Plant Physiology, 141, 1248-1254
  • Glawischnig E. (2006) The role of cytochrome P450 enzymes in the biosynthesis of camalexin. Biochem Soc Transactions, 34,1206-1208
  • Kriechbaumer V, Park WJ, Gierl A, Glawischnig E. (2006) Auxin biosynthesis in maize. Plant Biology, 8, 334-339
  • Kriechbaumer V, Glawischnig E. (2005) Auxin biosynthesis within the network of tryptophan metabolism. JNBT, 2, 55-58
  • Treml B, Winderl S, Radykewicz R, Herz M, Schweizer G, Hutzler P, Glawischnig E, Torres Ruiz RA. (2005) The gene ENHANCER OF PINOID controls cotyledon development in the Arabidopsis embryo. Development, 132, 4063-4074
  • Glawischnig E, Hansen BG, Olsen CE, Halkier BA. (2004) Camalexin is synthesized from indole-3-acetaldoxime, a key branching point between primary and secondary metabolism in Arabidopsis. Proc Natl Acad Sci USA, 101, 8245-8250
  • Adelsberger H, Hertel C, Glawischnig E, Zverlov VV, Schwarz WH. (2004) Enzyme system of Clostridium stercorarium for hydrolysis of arabinoxylan: reconstitution of the in vivo system from recombinant enzymes. Microbiology, 150, 2257-2266
  • Park WJ, Kriechbaumer V, Müller A, Piotrowski M, Meeley RB, Gierl A, Glawischnig E. (2003) The nitrilase ZmNIT2 converts indole-3-acetonitrile to indole-3-acetic acid. Plant Physiology, 133, 794-802
  • Glawischnig E, Mikkelsen MD, Halkier BA. (2003) Glucosinolate biosynthesis and metabolism. In Abrol Y., Altaf A. (Eds.) Sulphur in Higher Plants. Kluwer Academic Publishers, Dordrecht, NL
  • Chen S, Glawischnig E, Jørgensen K, Naur P, Jørgensen B, Olsen C-E, Hansen CH, Rasmussen H, Pickett JA, Halkier BA. (2003) CYP79F1 and CYP79F2 have distinct functions in the biosynthesis of aliphatic glucosinolates in Arabidopsis. Plant Journal, 33, 923-937
  • Mikkelsen MD, Petersen BL, Glawischnig E, Andreasson E, Jensen AB, Halkier BA. (2003) Modulation of CYP79 genes and glucosinolate profiles in Arabidopsis by defense signaling pathways. Plant Physiology, 131, 298-308
  • Glawischnig E, Gierl A, Tomas A, Bacher A, Eisenreich W. (2002) Starch biosynthesis and intermediary metabolism in maize kernels. Quantitative analysis of metabolite flux by NMR. Plant Physiology, 130, 1717-1727
  • Spiteller P, Glawischnig E, Gierl A, Steglich W. (2001) Studies on the biosynthesis of 2-hydroxy-1,4-benzoxazin-3-one (HBOA) from 3-hydroxyindolin-2-one in Zea mays. Phytochemistry, 57, 373-376
  • Glawischnig E, Gierl A, Tomas A, Bacher A, Eisenreich W. (2001) Retrobiosynthetic nuclear magnetic resonance analysis of amino acid biosynthesis and intermediary metabolism. Metabolic flux in developing maize kernels. Plant Physiology, 125, 1178-1186
  • Glawischnig E, Tomas A, Eisenreich W, Spiteller P, Bacher A, Gierl A. (2000) Auxin biosynthesis in maize kernels. Plant Physiology, 123, 1109-1119
  • Glawischnig E, Grün S, Frey M, Gierl A. (1999) Cytochrome P450 mono-oxygenases of DIBOA biosynthesis: Specificity and conservation among grasses. Phytochemistry, 50, 925-930
  • Glawischnig E, Eisenreich W, Bacher A, Frey M, Gierl A. (1997) Biosynthetic origin of oxygen atoms in DIMBOA from maize: NMR studies with 18O2. Phytochemistry, 45, 715-718
  • Frey M, Chomet P, Glawischnig E, Stettner C, Grün S, Winklmair A, Eisenreich W, Bacher A, Meeley R, Briggs SP, Simcox K, Gierl A. (1997) Analysis of a chemical plant defense mechanism in grasses. Science, 277, 696-699

 

Kontakt

Professur Mikrobielle Biotechnologie

Schulgasse 22
D-94315 Straubing

Leitung

Prof. Dr. Bastian Blombach

Tel.: +49 (0) 9421 187-420
Mail: bastian.blombach@tum.de

Sekretariat

Nancy Stüpfert

Tel.: +49 (0) 9421 187-425
Mail: nancy.stuepfert@tum.de